HBP1(Phospho Ser402) Polyclonal Antibody

Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5′-TTCATTCATTCA-3′. Binding to the H1F0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4.,Contains 1 AXH domain.,Contains 1 HMG box DNA-binding domain.,subunit:Binds the second PAH repeat of SIN3A (By similarity). Binds TCF4 and RB1.

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