EVSafe Lyophilization Buffer

Description

JOT-EV-LYOB is a lyophilization buffer formulated with an optimized combination of lyoprotectants that help to maintain EV integrity and biological activity while improving EV recovery during lyophilization. The buffer has been validated for its protective effect when lyophilizing EVs from diverse sources, including red blood cell-derived EVs, mesenchymal stromal cell-derived EVs, and plant-derived EVs. The components of this buffer have been carefully selected to be compatible with downstream EV experiments and do not include cell membrane-permeating reagents, protein-based cryoprotectants, synthetic polymers, lipid-based molecules or organic solvents. All the components in the storage buffer can be readily removed with a single centrifugation step (or any equivalent EV purification approach).

Link: Datasheet